Phospho-AS160 (Thr642) Antibody 44-1071G from Thermo Fisher Scientific

Product Specs
ItemPhospho-AS160 (Thr642) Antibody
CompanyThermo Fisher Scientific
Price Pricing Info Supplier Page View Company Product Page
Catalog Number44-1071G
Quantity100 µL
ApplicationsWestern Blot
Conjugate/TagUnconjugated
FormatDulbecco's PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide; pH 7.3
ReactivityHuman, Mouse
TargetPhospho-AS160 (Thr642)
IsotypeIgG
HostRabbit
ImmunogenThe antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human AS160 that contains threonine 642. The sequence is conserved in mouse
NCBI Full Gene NameTBC1 domain family member 4, TBC1 domain family, member 4
NCBI Gene AliasesAS160, A930035N22, 5930406J04Rik, As160, NIDDM5
ClonalityPolyclonal
ModificationsPhosphorylated: Thr642
Storage Temperature-20°C
PurityAntigen affinity chromatography
Antibody TypePrimary
Storage-20°C

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Thermo Fisher Scientific

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Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 DiabetesCell metabolismNovember 3, 2020Batista TM, Jayavelu AK, Wewer Albrechtsen NJ, Iovino S, Lebastchi J, Pan H, Dreyfuss JM, Krook A, Zierath JR, Mann M, et al.FOXO1 (#9454, Cell Signaling), FOXO3a (#12829, Cell Signaling), GLUT4 (ab654, Abcam), p-AS160T642 (44–1071G, Thermo Fisher Scientific), AS160 (# 2670, Cell Signaling), p-TSC2T1462 (# 3611, Cell Signaling), TSC2

(2) Inhibition of AMPK activity in response to insulin in adipocytes: involvement of AMPK pS485, PDEs, and cellular energy levelsAmerican journal of physiology. Endocrinology and metabolismSeptember 1, 2020Kopietz F, Rupar K, Berggreen C, Säll J, Vertommen D, Degerman E, Rider MH, Göransson O.

(3) Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic HomeostasisMolecular cellMay 4, 2017Meng ZX, Gong J, Chen Z, Sun J, Xiao Y, Wang L, Li Y, Liu J, Xu XZS, Lin JD.ab47283) and HDAC5 (1:1,000, ab1439) were from Abcam. Antibody against Phospho-AS160 (Thr642) (1:1,000, 44-1071G) was from Thermo Fisher. Immunofluorescence To study the translocation of endogenous HDAC5 in response

(4) Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet-Induced Insulin ResistanceDiabetesAugust 1, 2016Zhang W, Wu M, Kim T, Jariwala RH, Garvey WJ, Luo N, Kang M, Ma E, Tian L, Steverson D, et al.

(5) PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the HeartPloS oneJanuary 1, 2015Quan C, Xie B, Wang HY, Chen S.07–741) was from Millipore. The antibody that recognises phosphorylated Thr649 on AS160/TBC1D4 (Cat No. 441071G) was from Life Technologies. The GAPDH antibody (Cat No. G8795) was from Sigma, and the cTnT antibody

(6) TBC1D1 reduces palmitate oxidation by inhibiting β-HAD activity in skeletal muscleAmerican journal of physiology. Regulatory, integrative and comparative physiologyNovember 1, 2014Maher AC, McFarlan J, Lally J, Snook LA, Bonen A.

(7) 6-Mercaptopurine augments glucose transport activity in skeletal muscle cells in part via a mechanism dependent upon orphan nuclear receptor NR4A3American journal of physiology. Endocrinology and metabolismNovember 1, 2013Liu Q, Zhu X, Xu L, Fu Y, Garvey WT.

(8) Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscleAmerican journal of physiology. Endocrinology and metabolismMay 15, 2012Ducommun S, Wang HY, Sakamoto K, MacKintosh C, Chen S.

(9) Recovered insulin response by 2 weeks of leptin administration in high-fat fed rats is associated with restored AS160 activation and decreased reactive lipid accumulationAmerican journal of physiology. Regulatory, integrative and comparative physiologyJuly 1, 2011Stefanyk LE, Gulli RA, Ritchie IR, Chabowski A, Snook LA, Bonen A, Dyck DJ.

(10) Loss of 50% of excess weight using a very low energy diet improves insulin-stimulated glucose disposal and skeletal muscle insulin signalling in obese insulin-treated type 2 diabetic patientsDiabetologiaFebruary 1, 2008Jazet IM, Schaart G, Gastaldelli A, Ferrannini E, Hesselink MK, Schrauwen P, Romijn JA, Maassen JA, Pijl H, Ouwens DM, et al.

(11) Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed ratsDiabetesDecember 1, 2006Nascimento EB, Fodor M, van der Zon GC, Jazet IM, Meinders AE, Voshol PJ, Vlasblom R, Baan B, Eckel J, Maassen JA, et al.

(12) Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscleDiabetesJuly 1, 2006Kramer HF, Witczak CA, Fujii N, Jessen N, Taylor EB, Arnolds DE, Sakamoto K, Hirshman MF, Goodyear LJ.

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Phospho-AS160 (Thr642) Antibody from Thermo Fisher Scientific

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Phospho-AS160 (Thr642) Antibody from Thermo Fisher Scientific

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